Pregnancy causes various physiological and musculoskeletal changes that can result in orthopedic issues. Common complaints include low back pain, pelvic girdle pain, and carpal tunnel syndrome, largely due to hormonal shifts, weight gain, and changes in body mechanics. Osteoporosis may also occur, although less frequently, during pregnancy. The incidence of domestic violence and interpartner violence is notably higher in pregnant individuals. This review addresses the causes and management of orthopedic problems related to pregnancy, advocating for evidence-based diagnosis and treatment. It underscores the need for a multidisciplinary approach, involving obstetricians, orthopedic surgeons, endocrinologists, primary care physicians, and physical therapists, to effectively address these conditions.