Young individuals with moderate to severe periodontitis face not only oral health challenges but also significant psychological distress, which is often overlooked. A study involving 29 young patients with periodontitis and 30 healthy controls assessed periodontal health and psychological well-being using standardized anxiety and depression scales. Findings indicated that those with periodontitis had greater clinical attachment loss, probing depth, and higher scores for anxiety and depression compared to the controls. Factors such as female gender, higher education levels, smoking, and disease severity were identified as independent risk factors for anxiety. The research highlights that young adults with periodontitis are at an increased risk of psychological anxiety due to both biological and modifiable factors. The study suggests that personalized nursing education programs focusing on psychological support, smoking cessation, and targeted counseling are essential to alleviate the psychological burden and enhance treatment outcomes for these patients.