Meningitis continues to pose significant health risks for children aged 0-14, particularly in low- and middle-income countries, despite improvements in vaccines and healthcare. An analysis using Global Burden of Disease data from 1990 to 2021 found a 52% decline in global prevalence, a 69.2% drop in deaths, and a 69.1% reduction in disability-adjusted life years (DALYs). The highest disease burden in 2021 was noted in Sub-Saharan Africa and South Asia, with variations linked to the Socio-demographic Index (SDI). Major contributing factors to meningitis include malnutrition and behavioral issues. While the overall burden of meningitis has decreased, significant disparities remain between regions. Continued efforts in vaccination, strengthening health systems, and implementing targeted interventions in high-burden areas are essential to further reduce childhood mortality and disability linked to this disease.