Wrist exoskeletons are being developed to assist people with motor impairments like spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS). Current designs often lack the ability to adjust to individual wrist ranges of motion (ROM), which is essential for safety and usability. A study reviewed wrist abduction and adduction ROM measurements in individuals both with and without motor disabilities. It examined three groups: fifteen individuals without disabilities, two with ALS, and five with SCI. The study involved three trials to measure and analyze ROM, revealing that individuals without disabilities had the largest ROM range, while those with SCI showed reduced adduction. The findings emphasize the necessity for personalized ROM considerations in exoskeleton design to enhance functionality and prevent discomfort or injury. This research aims to advance the development of adjustable wrist exoskeletons, addressing existing safety and usability issues. The observed differences in ROM between users with and without disabilities highlight the importance of customizing exoskeletons to meet specific user needs, underscoring variability as a vital factor in rehabilitation.