A study published in the Asian Journal of Neurosurgery examined the effectiveness of mechanical thrombectomy (MT) combined with intravenous thrombolysis (IVT) in treating acute ischemic strokes, focusing on two age groups: those younger than 50 and those older. Researchers analyzed data from 500 patients who underwent the procedure, assessing factors related to favorable outcomes after treatment.

Results indicated that 144 patients were in the younger group with a mean age of 37.10 years, while 356 patients were older, with a mean age of 63.55 years. Significant differences emerged in medical histories, etiologies of strokes, and various outcomes between the two groups. Factors such as being younger than 50, a lower National Institute of Health Stroke Scale score at admission, and a recanalization time of less than four hours correlated with better clinical outcomes.

The study concluded that the combined technique of MT and IVT is safe and effective for anterior circulation strokes, with younger patients showing a higher likelihood of favorable outcomes and lower mortality rates within three months post-procedure.