In early childhood care settings, workers often adopt awkward postures and engage in repetitive tasks, which can lead to musculoskeletal disorders. A study aimed to develop a markerless method for estimating low back intersegmental moments during childcare activities, addressing the need for accurate and unobtrusive measurement techniques. Eight participants performed six manual handling and sit-to-stand tasks in a controlled lab environment using baby dummies of 2.7 kg and 10 kg. The new method, based solely on video recordings, was compared to a traditional approach that used marker-based motion capture and force platforms. The results showed mean absolute differences in joint moment estimation of about 20 Nm between the two methods, similar to errors found in other research using force platforms. This markerless technique does not require any instrumentation or extensive participant preparation, making it a practical tool for assessing low back intersegmental moments in real-world childcare scenarios.