A study evaluated the effects of single-incision mini-sling (SIMS) surgery on anxiety in women with moderate to severe stress urinary incontinence (SUI). Conducted at a tertiary urogynecology center, the research included 43 women assessed before and three months after surgery. The State-Trait Anxiety Inventory (STAI), International Consultation on Incontinence Questionnaire (ICIQ), and other measures were used to gauge outcomes. Excluded were women with previous incontinence surgeries or those on certain psychotropic medications. Results showed that 93% of participants achieved continence post-surgery, with the mean total STAI score decreasing significantly from 50.6 to 45.8. Notably, women with moderate SUI experienced a greater reduction in anxiety than those with severe SUI. While anxiety reduction did not significantly differ between SUI and mixed urinary incontinence (MUI) groups, MUI patients reported slightly lower satisfaction. The study concluded that SIMS leads to high continence rates and significant anxiety reduction, underscoring the need for integrating mental health assessments in urogynecologic care. Recommendations include preoperative STAI screening and ongoing tracking of patient-reported outcomes.