A rapid qualitative study explored the experiences of tuberculosis (TB) survivors with comorbidities in high-burden countries. Interviews conducted from August to October 2021 involved 24 participants, including 13 women, who had undergone treatment for either drug-susceptible or drug-resistant TB between 2015 and 2021. The participants experienced various comorbidities such as mental health disorders, diabetes, and HIV, with many reporting multiple health issues and socioeconomic challenges. The study found that TB treatment often worsened these comorbidities and led to increased mental health struggles, especially without integrated support.

Four key healthcare priorities emerged: early identification of comorbidities, timely and affordable access to care, tailored counseling and peer support, and coordinated care for TB and its associated comorbidities. The findings emphasize the need for a people-centered approach to healthcare that fosters trust among providers, ensures timely access to non-TB programs, and addresses the stigma associated with TB and its comorbidities. These priorities have been incorporated into the World Health Organization’s framework for collaborative action on TB and comorbidities.